G81R (p.Gly81Arg) variant of KRT3 (Keratin, type II cytoskeletal 3)
G81R (p.Gly81Arg) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G81R (p.Gly81Arg) variant details
- p.Gly81Arg
- ExAC rs749103210
- TOPMed rs749103210
- gnomAD rs749103210
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.51
- CADD 20.70
- PolyPhen-2 0.99
- SIFT 0.12
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available