G81A (p.Gly81Ala) variant of KRT3 (Keratin, type II cytoskeletal 3)
G81A (p.Gly81Ala) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G81A (p.Gly81Ala) variant details
- p.Gly81Ala
- 1000Genomes rs552886568
- ExAC rs552886568
- TOPMed rs552886568
- gnomAD rs552886568
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.52
- CADD 17.50
- PolyPhen-2 0.96
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available