G61D (p.Gly61Asp) variant of KRT3 (Keratin, type II cytoskeletal 3)
G61D (p.Gly61Asp) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G61D (p.Gly61Asp) variant details
- p.Gly61Asp
- ExAC rs756214553
- TOPMed rs756214553
- gnomAD rs756214553
- Missense
- Variant Prioritization Score for Impact Estimate 0.677
- REVEL 0.64
- CADD 24.50
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available