G106D (p.Gly106Asp) variant of KRT3 (Keratin, type II cytoskeletal 3)
G106D (p.Gly106Asp) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G106D (p.Gly106Asp) variant details
- p.Gly106Asp
- ExAC rs759827934
- TOPMed rs759827934
- gnomAD rs759827934
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.57
- CADD 22.50
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available