F131Y (p.Phe131Tyr) variant of KRT3 (Keratin, type II cytoskeletal 3)
F131Y (p.Phe131Tyr) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
F131Y (p.Phe131Tyr) variant details
- p.Phe131Tyr
- gnomAD rs1457866922
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.45
- CADD 13.00
- PolyPhen-2 0.33
- SIFT 1.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available