A21T (p.Ala21Thr) variant of KRT3 (Keratin, type II cytoskeletal 3)
A21T (p.Ala21Thr) in KRT3 (Keratin, type II cytoskeletal 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- TOPMed rs933468180
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.37
- CADD 19.80
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available