T37P (p.Thr37Pro) variant of KRT2 (P35908)
T37P (p.Thr37Pro) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T37P (p.Thr37Pro) variant details
- p.Thr37Pro
- ExAC rs749830972
- TOPMed rs749830972
- gnomAD rs749830972
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.28
- CADD 11.60
- PolyPhen-2 0.07
- SIFT 0.22
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available