S109R (p.Ser109Arg) variant of KRT2 (P35908)
S109R (p.Ser109Arg) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
S109R (p.Ser109Arg) variant details
- p.Ser109Arg
- TOPMed rs1334548837
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.18
- CADD 9.05
- PolyPhen-2 0.02
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available