G97R (p.Gly97Arg) variant of KRT2 (P35908)
G97R (p.Gly97Arg) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G97R (p.Gly97Arg) variant details
- p.Gly97Arg
- ExAC rs776998809
- gnomAD rs776998809
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.56
- CADD 18.80
- PolyPhen-2 0.42
- SIFT 0.07
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available