G88R (p.Gly88Arg) variant of KRT2 (P35908)
G88R (p.Gly88Arg) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
G88R (p.Gly88Arg) variant details
- p.Gly88Arg
- ExAC rs755992166
- TOPMed rs755992166
- gnomAD rs755992166
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.52
- CADD 15.60
- PolyPhen-2 0.28
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available