G88* (p.Gly88Ter) variant of KRT2 (P35908)
G88* (p.Gly88Ter) in KRT2 (P35908) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
G88* (p.Gly88Ter) variant details
- p.Gly88Ter
- ExAC rs755992166
- TOPMed rs755992166
- gnomAD rs755992166
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.818
- CADD 35.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available