G84D (p.Gly84Asp) variant of KRT2 (P35908)
G84D (p.Gly84Asp) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
G84D (p.Gly84Asp) variant details
- p.Gly84Asp
- ExAC rs746380399
- gnomAD rs746380399
- Missense
- Variant Prioritization Score for Impact Estimate 0.492
- REVEL 0.41
- CADD 20.70
- PolyPhen-2 0.58
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available