G31A (p.Gly31Ala) variant of KRT2 (P35908)
G31A (p.Gly31Ala) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
G31A (p.Gly31Ala) variant details
- p.Gly31Ala
- TOPMed rs1329013108
- gnomAD rs1329013108
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.25
- CADD 18.10
- PolyPhen-2 0.01
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available