G21S (p.Gly21Ser) variant of KRT2 (P35908)
G21S (p.Gly21Ser) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G21S (p.Gly21Ser) variant details
- p.Gly21Ser
- Ensembl rs1941263789
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.26
- CADD 17.10
- PolyPhen-2 0.03
- SIFT 0.14
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available