G15S (p.Gly15Ser) variant of KRT2 (P35908)
G15S (p.Gly15Ser) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G15S (p.Gly15Ser) variant details
- p.Gly15Ser
- TOPMed rs1388086081
- gnomAD rs1388086081
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.38
- CADD 19.60
- PolyPhen-2 0.27
- SIFT 0.33
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available