G115E (p.Gly115Glu) variant of KRT2 (P35908)
G115E (p.Gly115Glu) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G115E (p.Gly115Glu) variant details
- p.Gly115Glu
- gnomAD rs1214663922
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.36
- CADD 21.70
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available