G110S (p.Gly110Ser) variant of KRT2 (P35908)
G110S (p.Gly110Ser) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G110S (p.Gly110Ser) variant details
- p.Gly110Ser
- gnomAD rs1160658410
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.26
- CADD 16.60
- PolyPhen-2 0.20
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available