F19S (p.Phe19Ser) variant of KRT2 (P35908)
F19S (p.Phe19Ser) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
F19S (p.Phe19Ser) variant details
- p.Phe19Ser
- ExAC rs753933142
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.27
- CADD 12.30
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available