A86S (p.Ala86Ser) variant of KRT2 (P35908)
A86S (p.Ala86Ser) in KRT2 (P35908) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A86S (p.Ala86Ser) variant details
- p.Ala86Ser
- ExAC rs779847057
- TOPMed rs779847057
- gnomAD rs779847057
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.20
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available