G25C (p.Gly25Cys) variant of KRT18 (Keratin, type I cytoskeletal 18)
G25C (p.Gly25Cys) in KRT18 (Keratin, type I cytoskeletal 18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G25C (p.Gly25Cys) variant details
- p.Gly25Cys
- cosmic curated COSV66316
- ExAC rs750200705
- gnomAD rs750200705
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.22
- CADD 11.60
- PolyPhen-2 0.02
- SIFT 0.19
- Population evidence available
- Structural context available