T87I (p.Thr87Ile) variant of KRT17 (Keratin, type I cytoskeletal 17)
T87I (p.Thr87Ile) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
T87I (p.Thr87Ile) variant details
- p.Thr87Ile
- gnomAD rs1265695783
- Missense
- Variant Prioritization Score for Impact Estimate 0.777
- REVEL 0.84
- CADD 27.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available