S25Y (p.Ser25Tyr) variant of KRT17 (Keratin, type I cytoskeletal 17)
S25Y (p.Ser25Tyr) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
S25Y (p.Ser25Tyr) variant details
- p.Ser25Tyr
- Ensembl rs1908658723
- Missense
- Variant Prioritization Score for Impact Estimate 0.537
- REVEL 0.54
- CADD 24.40
- PolyPhen-2 0.72
- SIFT 0.02
- Population evidence available
- Structural context available