R26H (p.Arg26His) variant of KRT17 (Keratin, type I cytoskeletal 17)
R26H (p.Arg26His) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R26H (p.Arg26His) variant details
- p.Arg26His
- ExAC rs745486930
- TOPMed rs745486930
- gnomAD rs745486930
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.39
- CADD 18.80
- PolyPhen-2 0.29
- SIFT 0.23
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available