M88I (p.Met88Ile) variant of KRT17 (Keratin, type I cytoskeletal 17)
M88I (p.Met88Ile) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
M88I (p.Met88Ile) variant details
- p.Met88Ile
- TOPMed rs1205697518
- gnomAD rs1205697518
- Missense
- Variant Prioritization Score for Impact Estimate 0.778
- REVEL 0.80
- CADD 24.20
- PolyPhen-2 0.34
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available