G75D (p.Gly75Asp) variant of KRT17 (Keratin, type I cytoskeletal 17)
G75D (p.Gly75Asp) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G75D (p.Gly75Asp) variant details
- p.Gly75Asp
- ExAC rs760378776
- gnomAD rs760378776
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.10
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available