G74V (p.Gly74Val) variant of KRT17 (Keratin, type I cytoskeletal 17)
G74V (p.Gly74Val) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
G74V (p.Gly74Val) variant details
- p.Gly74Val
- ExAC rs200102896
- TOPMed rs200102896
- gnomAD rs200102896
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.46
- CADD 14.00
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available