G66S (p.Gly66Ser) variant of KRT17 (Keratin, type I cytoskeletal 17)
G66S (p.Gly66Ser) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G66S (p.Gly66Ser) variant details
- p.Gly66Ser
- TOPMed rs1477627658
- gnomAD rs1477627658
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.39
- CADD 20.70
- PolyPhen-2 0.23
- SIFT 0.19
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available