G22R (p.Gly22Arg) variant of KRT17 (Keratin, type I cytoskeletal 17)
G22R (p.Gly22Arg) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- TOPMed rs1387497386
- gnomAD rs1387497386
- Missense
- Variant Prioritization Score for Impact Estimate 0.568
- REVEL 0.56
- CADD 22.80
- PolyPhen-2 0.95
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available