G21R (p.Gly21Arg) variant of KRT17 (Keratin, type I cytoskeletal 17)
G21R (p.Gly21Arg) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
G21R (p.Gly21Arg) variant details
- p.Gly21Arg
- gnomAD rs1366910575
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.50
- CADD 24.10
- PolyPhen-2 0.67
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available