D77G (p.Asp77Gly) variant of KRT17 (Keratin, type I cytoskeletal 17)
D77G (p.Asp77Gly) in KRT17 (Keratin, type I cytoskeletal 17) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
D77G (p.Asp77Gly) variant details
- p.Asp77Gly
- TOPMed rs1218892088
- gnomAD rs1218892088
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.20
- CADD 19.00
- PolyPhen-2 0.02
- SIFT 0.21
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available