S10P (p.Ser10Pro) variant of KRT14 (Keratin, type I cytoskeletal 14)
S10P (p.Ser10Pro) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
S10P (p.Ser10Pro) variant details
- p.Ser10Pro
- gnomAD rs1374827316
- Missense
- Variant Prioritization Score for Impact Estimate 0.609
- REVEL 0.60
- CADD 27.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available