K15R (p.Lys15Arg) variant of KRT14 (Keratin, type I cytoskeletal 14)
K15R (p.Lys15Arg) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K15R (p.Lys15Arg) variant details
- p.Lys15Arg
- gnomAD rs1318809672
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.25
- CADD 22.70
- PolyPhen-2 0.06
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available