K15E (p.Lys15Glu) variant of KRT14 (Keratin, type I cytoskeletal 14)
K15E (p.Lys15Glu) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
K15E (p.Lys15Glu) variant details
- p.Lys15Glu
- gnomAD rs1455415891
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- REVEL 0.36
- CADD 26.20
- PolyPhen-2 0.55
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available