G91D (p.Gly91Asp) variant of KRT14 (Keratin, type I cytoskeletal 14)
G91D (p.Gly91Asp) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G91D (p.Gly91Asp) variant details
- p.Gly91Asp
- rs1450806388
- TOPMed rs1450806388
- gnomAD rs1450806388
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.51
- CADD 22.00
- PolyPhen-2 0.93
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available