G89D (p.Gly89Asp) variant of KRT14 (Keratin, type I cytoskeletal 14)
G89D (p.Gly89Asp) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G89D (p.Gly89Asp) variant details
- p.Gly89Asp
- ExAC rs778192358
- TOPMed rs778192358
- gnomAD rs778192358
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- REVEL 0.51
- CADD 22.90
- PolyPhen-2 0.98
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available