G85W (p.Gly85Trp) variant of KRT14 (Keratin, type I cytoskeletal 14)
G85W (p.Gly85Trp) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G85W (p.Gly85Trp) variant details
- p.Gly85Trp
- TOPMed rs1280526971
- gnomAD rs1280526971
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.34
- CADD 20.10
- PolyPhen-2 0.22
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available