G85R (p.Gly85Arg) variant of KRT14 (Keratin, type I cytoskeletal 14)
G85R (p.Gly85Arg) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G85R (p.Gly85Arg) variant details
- p.Gly85Arg
- TOPMed rs1280526971
- gnomAD rs1280526971
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.35
- CADD 15.30
- PolyPhen-2 0.13
- SIFT 0.08
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available