G66R (p.Gly66Arg) variant of KRT14 (Keratin, type I cytoskeletal 14)
G66R (p.Gly66Arg) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
G66R (p.Gly66Arg) variant details
- p.Gly66Arg
- ExAC rs749619996
- gnomAD rs749619996
- Missense
- Variant Prioritization Score for Impact Estimate 0.619
- REVEL 0.58
- CADD 22.10
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available