G61A (p.Gly61Ala) variant of KRT14 (Keratin, type I cytoskeletal 14)
G61A (p.Gly61Ala) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G61A (p.Gly61Ala) variant details
- p.Gly61Ala
- Ensembl rs1907543032
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.34
- CADD 10.00
- PolyPhen-2 0.13
- SIFT 0.36
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available