G60R (p.Gly60Arg) variant of KRT14 (Keratin, type I cytoskeletal 14)
G60R (p.Gly60Arg) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
G60R (p.Gly60Arg) variant details
- p.Gly60Arg
- TOPMed rs1367015717
- gnomAD rs1367015717
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.58
- CADD 16.70
- PolyPhen-2 0.33
- SIFT 0.18
- Most common in the Latino/Admixed American population (allele frequency 7.1e-05)
- Structural context available