G37R (p.Gly37Arg) variant of KRT14 (Keratin, type I cytoskeletal 14)
G37R (p.Gly37Arg) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G37R (p.Gly37Arg) variant details
- p.Gly37Arg
- rs1312208815
- NCI-TCGA Cosmic COSV5142
- TOPMed rs1312208815
- gnomAD rs1312208815
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.23
- CADD 15.90
- PolyPhen-2 0.01
- SIFT 0.15
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 5.6e-05)
- Structural context available