G25E (p.Gly25Glu) variant of KRT14 (Keratin, type I cytoskeletal 14)
G25E (p.Gly25Glu) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
G25E (p.Gly25Glu) variant details
- p.Gly25Glu
- TOPMed rs1327472230
- gnomAD rs1327472230
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.15
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Middle Eastern population (allele frequency 0.00024)
- Structural context available