G21E (p.Gly21Glu) variant of KRT14 (Keratin, type I cytoskeletal 14)
G21E (p.Gly21Glu) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G21E (p.Gly21Glu) variant details
- p.Gly21Glu
- gnomAD rs1215846581
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.26
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.5e-05)
- Structural context available