G106S (p.Gly106Ser) variant of KRT14 (Keratin, type I cytoskeletal 14)
G106S (p.Gly106Ser) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G106S (p.Gly106Ser) variant details
- p.Gly106Ser
- Ensembl rs1907532993
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.29
- CADD 11.00
- PolyPhen-2 0.01
- SIFT 0.35
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available