G106A (p.Gly106Ala) variant of KRT14 (Keratin, type I cytoskeletal 14)
G106A (p.Gly106Ala) in KRT14 (Keratin, type I cytoskeletal 14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G106A (p.Gly106Ala) variant details
- p.Gly106Ala
- Ensembl rs2144586141
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.25
- CADD 1.66
- PolyPhen-2 0.02
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available