S153N (p.Ser153Asn) variant of KRT13 (Keratin, type I cytoskeletal 13)
S153N (p.Ser153Asn) in KRT13 (Keratin, type I cytoskeletal 13) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes structural context.
S153N (p.Ser153Asn) variant details
- p.Ser153Asn
- rs375114873
- NCI-TCGA Cosmic COSV5584
- cosmic curated COSV99877
- ESP rs375114873
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.531
- AlphaMissense 0.09
- MetaLR 0.70
- MetaSVM 0.03
- PolyPhen-2 0.77
- SIFT 0.01
- MutPred 0.57
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available