L77F (p.Leu77Phe) variant of KRT13 (Keratin, type I cytoskeletal 13)
L77F (p.Leu77Phe) in KRT13 (Keratin, type I cytoskeletal 13) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
L77F (p.Leu77Phe) variant details
- p.Leu77Phe
- ExAC rs770760776
- Missense
- Variant Prioritization Score for Impact Estimate 0.153
- REVEL 0.20
- CADD 3.46
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available