L141P (p.Leu141Pro) variant of KRT13 (Keratin, type I cytoskeletal 13)
L141P (p.Leu141Pro) in KRT13 (Keratin, type I cytoskeletal 13) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L141P (p.Leu141Pro) variant details
- p.Leu141Pro
- TOPMed rs1229563475
- gnomAD rs1229563475
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.36
- CADD 2.59
- PolyPhen-2 0.06
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available