G83E (p.Gly83Glu) variant of KRT13 (Keratin, type I cytoskeletal 13)
G83E (p.Gly83Glu) in KRT13 (Keratin, type I cytoskeletal 13) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G83E (p.Gly83Glu) variant details
- p.Gly83Glu
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.37
- CADD 21.60
- PolyPhen-2 0.98
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available