F61L (p.Phe61Leu) variant of KRT13 (Keratin, type I cytoskeletal 13)
F61L (p.Phe61Leu) in KRT13 (Keratin, type I cytoskeletal 13) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
F61L (p.Phe61Leu) variant details
- p.Phe61Leu
- cosmic curated COSV10720
- Ensembl rs1393841091
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.13
- CADD 13.70
- PolyPhen-2 0.00
- SIFT 0.73
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available